Postdoctoral researcher – GPCR mechanosensing

About the role

The Mathiasen Group at the Department of Biomedical Sciences, University of Copenhagen, is seeking a motivated postdoctoral researcher to join the GPCRmec project, a Novo Nordisk Foundation‑funded initiative investigating GPCR mechanosensation. The position starts on 1 October 2026 (or as soon as possible thereafter) and lasts for one year.

Key responsibilities

• Develop and implement novel fluorescence‑based assays to study GPCR oligomerization and mechanosensation at the subcellular level.
• Perform confocal and other fluorescence imaging experiments on live mammalian cells.
• Conduct GPCR signalling assays and analyse data to elucidate mechanisms of mechanical stress response.
• Collaborate with researchers at the Niels Bohr Institute and the Department of Chemistry for cross‑disciplinary expertise and microscopy access.
• Prepare scientific reports, present findings, and contribute to peer‑reviewed publications.

Required profile

• PhD (or equivalent) in Biophysics, Molecular/Cell Biology, Biochemistry, Life Sciences or a related field.
• Proven experience with confocal and fluorescence imaging techniques.
• Experience investigating GPCR signalling, function, and oligomerization.
• Skilled in mammalian cell culture and standard molecular biology methods.
• Strong communication skills and ability to work collaboratively with MSc and PhD students.
• Excellent written and spoken English.

Required skills

• Confocal imaging
• Fluorescence microscopy
• GPCR signalling assays
• Cell culture (mammalian)
• Molecular biology techniques

What we offer

• A dynamic, interdisciplinary research environment with international colleagues.
• Access to state‑of‑the‑art microscopy facilities.
• Collaboration across multiple institutions.
• One‑year fixed‑term contract funded by the Novo Nordisk Foundation.