Postdoctoral Scientist – Lipid Nanoparticle High‑Throughput Screening

About the role

We are seeking a detail‑oriented postdoctoral scientist to lead the development and optimisation of high‑throughput lipid nanoparticle (LNP) formulation workflows. The position is based at the Novo Nordisk Foundation Initiative for Vaccines and Immunity (NIVI) Research Center, University of Copenhagen, and will support vaccine candidate development against respiratory pathogens.

Key responsibilities

• Design, implement and optimise LNP barcoding and high‑throughput screening pipelines using molecular barcodes and next‑generation sequencing.
• Develop automated liquid‑handling and robotic protocols for large‑scale in‑vitro and in‑vivo assays.
• Apply Design of Experiments (DOE) and statistical modelling to guide formulation optimisation.
• Integrate wet‑lab and dry‑lab data streams, including machine‑learning approaches for data interpretation.
• Collaborate with immunology and microbiology teams to translate screening results into vaccine candidates.

Required profile

• PhD in molecular biology, biotechnology, bioengineering, bioinformatics, chemistry or a related discipline.
• Minimum three years of hands‑on experience with high‑throughput LNP screening and next‑generation sequencing.
• Strong understanding of mRNA delivery mechanisms and targeted delivery systems.

Required skills

• Lipid nanoparticle formulation and screening
• Next‑generation sequencing
• Automated liquid‑handling and robotic workflow automation
• Molecular barcoding and multiplexed sample handling
• Design of Experiments (DOE)
• Data modelling, visualization and statistical analysis
• Machine‑learning techniques for high‑throughput data

What we offer

• Access to state‑of‑the‑art instrumentation and core facilities.
• Collaborative environment within a leading vaccine research centre.
• Opportunities for authorship and participation in high‑impact publications.